Mikrobiyom alanında öne çıkan güncel bilimsel yayınların derlendiği bir literatür seçkisi sunuyoruz.
İnsan Mikrobiyomu
Elucidation of population-based bacterial adaptation to antimicrobial treatment by single-cell sequencing analysis of the gut microbiome of a hospital patient. Ye, L., Wu, Y., Guo, J., Wang, H., Cai, J., Chen, K., Dong, N., Yu, J., Chao, S., Zhou, H., Chen, G., Chen, S., & Zhang, R. (2025). mSystems, e0163124. https://doi.org/10.1128/msystems.01631-24
Prominent mediatory role of gut microbiome in the effect of lifestyle on host metabolic phenotypes. Prifti, E., Aron-Wisnewsky, J., Chakaroun, R., Nielsen, T., Poitou, C., Bel-Lassen, P., Rouault, C., Le Roy, T., Andrikopoulos, P., Chechi, K., Puig-Castellví, F., Dionicio, I. C., Froguel, P., Holmes, B., Alili, R., Andreelli, F., … Clément, K. (2025). Gut Microbes, 17(1). https://doi.org/10.1080/19490976.2025.2599565
Lactobacillus salivarius HHuMin-U attenuates vulvovaginal candidiasis via vaginal epithelial immune enhancement mediated by NF-κB activation. Choi, J., Jo, J. Y., Lee, J. S., Son, J. E., Kim, S. Y., Lee, H. E., Seong, Y. J., Heo, K., Kim, Y., Park, M. S., & Byun, S. (2025). New biotechnology, 90, 36–47. https://doi.org/10.1016/j.nbt.2025.08.003
Metabolic modeling links gut microbiota to metabolic markers of Parkinson's disease Hensen, T., & Thiele, I. (2025). Gut Microbes, 17(1), 2554195. https://doi.org/10.1080/19490976.2025.2554195
The dysbiosis of intestinal microbiota associated with isolated tricuspid valve regurgitation. Ge, T., Fang, D., Zhong, L. et al. (2025). J Cardiothorac Surg. https://doi.org/10.1186/s13019-025-03786-z
Targeting gut microbiota with short-chain fructo-oligosaccharides prebiotic fibers to support metabolic health in overweight prediabetic adults: a randomized, double-blinded, placebo-controlled study. Le Bourgot, C., Capronnier, O., Graf, S., & Carton, T. (2025). Frontiers in nutrition, 12, 1718169. https://doi.org/10.3389/fnut.2025.1718169
Human and bacterial genetic variation shape oral microbiomes and health Kamitaki, N., Handsaker, R.E., Hujoel, M.L.A. et al. (2026). Nature https://doi.org/10.1038/s41586-025-10037-7
Hayvan Mikrobiyomu
High-Altitude Extreme Environments Drive Convergent Evolution of Skin Microbiota in Humans and Horses. Zhang, Y., Zhang, M., Zhao, Z., Peng, Y., Deng, F., Jiang, H., Zhang, M., Song, B., Kim, J. K., Pan, J. H., Chai, J., & Li, Y. (2026). Microorganisms, 14(1), 57. https://doi.org/10.3390/microorganisms14010057
Antibiotic-Mediated Microbiota Depletion of Aedes aegypti Gut Bacteria Modulates Susceptibility to Entomopathogenic Fungal Infection and Modifies Developmental Factors. Ribeiro, J. P., Paula, A. R. d., Silva, L. E. I., Silva, G. A., Silva, C. P., Butt, T. M., & Samuels, R. I. (2026). Parasitologia, 6(1), 4. https://doi.org/10.3390/parasitologia6010004
Bitki Mikrobiyomu
Host plants shape rhizosphere microbiomes to counteract Fusarium: molecular mechanisms and translational strategies Fang, D., He, S., Li, L., Zhou, M., Gao, Z., Zhang, S., & Li, X. (2025). Physiological and Molecular Plant Pathology, 103044. https://doi.org/10.1016/j.pmpp.2025.103044
Decoding Plant-Microbe Interactions through the Kiwifruit Microbiome in Bacterial Canker Disease. Yang, X. G., Yan, Y. W., Zhang, X. X., Su, Y., Chen, M. X., & Li, X. Y. (2025). Journal of agricultural and food chemistry, 10.1021/acs.jafc.5c12587. Advance online publication. https://doi.org/10.1021/acs.jafc.5c12587
Çevresel Mikrobiyom
Mechanisms of Fish Intestinal Damage Under Environmental Stress: Insights From Carbonate Saline–Alkali Water Perspective. Jia Rui Cui, Yi Fang Lai, Yue-Hong Li (2026). Reviews in Aquaculture. https://doi.org/10.1111/raq.70118
Dynamic succession and biodegradation potential of microplastic prokaryotic microbial communities in the Pearl River estuary. Yan, W., Tang, D., Ahmad, M., Wang, P., Li, J., Peng, Z., & Li, W. (2026). Marine Pollution Bulletin, 223, 118992. https://doi.org/10.1016/j.marpolbul.2025.118992
Fertilizer level has a stronger effect than tillage intensity on crop microbiome recruitment. Dasgupta, D., Camuy-Vélez, L. A., Nath, D., Zitnick-Anderson, K., Aberle, E., & Banerjee, S. (2026). Agriculture, Ecosystems & Environment, 399, 110144. https://doi.org/10.1016/j.agee.2025.110144
From Gut to Brain: Glyphosate and Triclosan Impair Microbiome Composition, Neuroactive Metabolites, and Cognitive and Ecological Fitness in Daphnia magna. Irene Romero-AlfanoAlba Julia LópezBenjamin PiñaCristian Gómez-CanelaCarlos Barata (2026). Environmental Science & Technology. https://doi.org/10.1021/acs.est.5c15302
Yeni Yöntemler
DANSE: a pipeline for dynamic modelling of time-series multi-omics data. Jansen Klomp, L. F., Yan, X., Snabel, R. R., Veenstra, G. J. C., Meijer, H. G. E., & Post, J. N. (2025). BMC bioinformatics, 10.1186/s12859-025-06354-3. Advance online publication. https://doi.org/10.1186/s12859-025-06354-3
Cleanifier: contamination removal from microbial sequences using spaced seeds of a human pangenome index. Zentgraf, J., Schmitz, J. E., & Rahmann, S. (2026). Bioinformatics (Oxford, England), 42(1), btaf632. https://doi.org/10.1093/bioinformatics/btaf632
EXPLANA: a user-friendly workflow for EXPLoratory ANAlysis and feature selection in cross-sectional and longitudinal microbiome studies. Fouquier, J., Stanislawski, M., O'Connor, J., Scadden, A., & Lozupone, C. (2026). Bioinformatics (Oxford, England), 42(1), btaf658. https://doi.org/10.1093/bioinformatics/btaf658
Advancing regulatory variant effect prediction with AlphaGenome. Avsec, Ž., Latysheva, N., Cheng, J. et al. (2026) Nature 649, 1206–1218. https://doi.org/10.1038/s41586-025-10014-0
