Mikrobiyom alanında öne çıkan güncel bilimsel yayınların haftalık olarak derlendiği bir literatür seçkisi sunuyoruz.
İnsan Mikrobiyomu
Gut microbiota predictive of the efficacy of consolidation immunotherapy and chemoradiotherapy toxicity in lung cancer. Wu, L., Li, Y., Wang, W., Deng, L., Ge, H., Cui, M., & Bi, N. (2025). Med, 6-12. https://doi.org/10.1016/j.medj.2025.100877
The gut microbiota as a potential biomarker in patients with EGFR-mutant lung cancer. Tabe, C., Motooka, D., Fujita, T. et al. The gut microbiota as a potential biomarker in patients with EGFR-mutant lung cancer. Sci Rep (2025). https://doi.org/10.1038/s41598-025-31225-5
RNA, reuse, recycle: the analysis of multiple known human microbiome communities using unmapped next-generation sequencing data. Wainwright, F., Mısırlı, G., & Andras, P. (2025). Advanced Gut & Microbiome Research, 2025(1), 7232239. https://doi.org/10.1155/agm3/7232239
Gut micro-organisms associated with health, nutrition and dietary interventions. Asnicar, F., Manghi, P., Fackelmann, G. et al. Gut micro-organisms associated with health, nutrition and dietary interventions. Nature (2025). https://doi.org/10.1038/s41586-025-09854-7
Hayvan Mikrobiyomu
Microbial metabolite trimethylamine-N-oxide facilitates colorectal inflammation-cancer transformation by blocking lysosomal degradation of Wnt signaling. Yang, K., Liu, Z., Wang, H., Xiao, Z., Zhao, W., & Gong, W. (2025). Gut Microbes, 17-1. https://doi.org/10.1080/19490976.2025.2597626
Lotus leaf extract (LLE) alleviates obesity through gut flora and its metabolites. Wang, T., Yang, Y., Hou, J., & Yin, L. (2025). Food chemistry, 495(Pt 3), 146433. https://doi.org/10.1016/j.foodchem.2025.146433
Whey Protein Phospholipid Concentrate and Its Fractions as a Diet Intervention Enhance Bone Health and Alter the Gut Microbiome in Weanling Mice. Armstrong, M. T., Antunes, K., Willis, N. B., Meyer, M. B., Pierre, J. F., & Ozturk, G. (2025). FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 39(23), e71260. https://doi.org/10.1096/fj.202502683R
Metatranscriptomic insights into feeding preferences, bacterial diversity, and insect-specific viruses genomics in Aedes aegypti populations from Ibagué, Colombia Zabaleta WDB, Gomez JDR, Santofimio Villa LF, Angarita NB, Alzate JF, Garzón YEG, Cantillo-Barraza O, Triana-Chavez O, Vargas PAO, Urrea DA. (2025) Acta Trop. D273:107941. https://doi.org/10.1016/j.actatropica.2025.107941
Bitki Mikrobiyomu
Cross-talk within plant niches: endophytic and arbuscular mycorrhizal fungi for sustainable crop production. Orozco-Mosqueda, M. D. C., Glick, B. R., & Santoyo, G. (2025). FEMS Microbiology Reviews, fuaf063. https://doi.org/10.1093/femsre/fuaf063
Calcium-containing inorganic immunity booster drives the enrichment of specific root endophytic microbiota against Ralstonia solanacearum. Bi J, Wei B, Wang E, Zeng X, Liu X, Sun M, Wei H, Li S, Chen M, Peng J, Song A, Yi K, Fan F. (2025). Microbiome. https://doi.org/10.1186/s40168-025-02228-1
Çevresel Mikrobiyom
Metagenomics insights into the functional traits and risk surveillance of ballast water microbiome from a genome-centric perspective. Lv, B., Kan, G., Mei, S., Han, Y., Jiang, C., Cui, Y., & Shi, J. (2025). Process Safety and Environmental Protection, 108317. https://doi.org/10.1016/j.psep.2025.108317
Environmental and microbial drivers of global rhizosphere resistome assembly. Yang H, Yu Y, Cui R, Zhang Q, Chen B, Zhang Z, Xu N, Sun L, Lu T, Qian H. (2025). Journal of Agricultural and Food Chemistry. https://doi.org/10.1021/acs.jafc.5c11060
Harnessing haloarchaea from halophyte Atriplex nummularia rhizosphere to enhance salt stress tolerance in maize seedlings. Ventura JP, Lacerda-Júnior GV, Rados T, Bisson A, Fernandes-Júnior PI, Melo IS. (2025) Environmental Microbiome. https://doi.org/10.1186/s40793-025-00698-2
Yeni Yöntemler
Scikit-bio: a fundamental Python library for biological omic data analysis. Aton, M., McDonald, D., Cañardo Alastuey, J., Azom, R., Batra, P., Bezshapkin, V., ... & Zhu, Q. (2025). Nature Methods, 1-3. https://doi.org/10.1038/s41592-025-02981-z
Transcript-guided targeted cell enrichment for scalable single-nucleus RNA sequencing. Liao, A., Zhang, Z., Sziraki, A., Abdulraouf, A., Rehman, A., Xu, Z., Lu, Z., Jiang, W., Arya, A., Lee, J., Maragkakis, M., Zhou, W., & Cao, J. (2025). Cell genomics, 101101. https://doi.org/10.1016/j.xgen.2025.101101
An integrative multi-omics random forest framework for robust biomarker discovery. Zhang, W., Huang, H., Wang, L., Lehmann, B. D., & Chen, X. S. (2025). GigaScience, giaf148. https://doi.org/10.1093/gigascience/giaf148
gutMSNP: a comprehensive database for human gut microbial single-nucleotide polymorphisms. Kai Qian, Meiyu Du, Senwei Tan, Mingyang Ding, Meihui Song, Minke Lu, Changlu Qi, Liang Cheng, Xue Zhang (2025). Nucleic Acids Research, gkaf1205, https://doi.org/10.1093/nar/gkaf1205
