Mikrobiyom alanında öne çıkan güncel bilimsel yayınların haftalık olarak derlendiği bir literatür seçkisi sunuyoruz.
İnsan Mikrobiyomu
Meta-analysis of 22,710 human microbiome metagenomes defines an oral-to-gut microbial enrichment score and associations with host health and disease. Manghi, P., Antonello, G., Schiffer, L. et al. (2025) Nat Commun. https://doi.org/10.1038/s41467-025-66888-1
Functional dynamics between resident transcriptionally active microbes (TAMs) and host genes underlie Dengue severity. Kumari, P., Devi, P., Banerjee, B., Tarai, B., Budhiraja, S., Sethi, T. P., & Pandey, R. (2025). Gut Microbes, 19-12 https://doi.org/10.1371/journal.pntd.0013836
Integrated multi-omic and symptom clustering reveals lower-gastrointestinal disorders of gut-brain interaction heterogeneity. Dowrick, J. M., Roy, N. C., Carco, C., James, S. C., Heenan, P. E., Frampton, C. M. A., Fraser, K., Young, W., Cooney, J., Trower, T., Keenan, J. I., McNabb, W. C., Mullaney, J. A., Bayer, S. B., Talley, N. J., Gearry, R. B., & Angeli-Gordon, T. R. (2026). Gut Microbes, 18-1. https://doi.org/10.1080/19490976.2025.2604871
Supplementation with a Limosilactobacillus fermentum K73 synbiotic modulates gut microbiota function and behavior in gnotobiotic mice transplanted with microbiota from children diagnosed with autism spectrum disorder. Estrada, K. B., Azamar, K. M. M., Wang, C., Sudi, S. D., Friday-Saunders, K., Márquez, V., … Alviña, K. (2025). OpenRxiv. https://doi.org/10.64898/2025.12.16.694732
Universal-Bac 3 Gel ®: a 3D biofilm-relevant matrix that supports in vitro growth and biofilm formation of ESKAPE pathogens. Peluso, E., Van Uden, S., Visentin, S., Petrini, P., Pacheco, D. P., & Visai, L. (2025). OpenRxiv. https://doi.org/10.64898/2025.12.16.694620
Hayvan Mikrobiyomu
Single-cell analysis of testicular bacterial microbiome changes during aging and effect on reproductive capacity in mice Zhou, J., Li, Y., Zhu, T., Yang, K., Zhang, C., Zhang, R., ... & Zhu, Z. (2025). IScience. https://doi.org/10.1016/j.isci.2025.114174
The relationships between box turtle gut microbiomes and personality. Harlow, K., Service, E. K., Geiger, J. E., Carlson, B. E., & Kimble, S. J. A. (2025). PLoS ONE, e0339132. https://doi.org/10.1371/journal.pone.0339132
Next-generation sequencing insights into the oral microbiome and antibiotic resistance genes in grey wolves (Canis lupus). Sakarnyte, L., Spinkyte, R., Merkeviciene, L., Siugzdiniene, R., & Ruszauskas, M. (2025). Animals, 3639. https://doi.org/10.3390/ani15243639
Bitki Mikrobiyomu
The tomato seed microbiome is mainly shaped by host genotype and production site. Chen, X., Olimi, E., Lobato, C., Berg, G., & Cernava, T. (2025). mSystems, e0144125. https://doi.org/10.1128/msystems.01441-25
Interplay between host and environmental filters drives plant-associated microbiomes in the remote sub-Antarctic Kerguelen Islands. Bertrand, C., Marmeisse, R., Martin, M. C., & Binet, F. (2025). Environmental Microbiome, 20(1), 154. https://doi.org/10.1186/s40793-025-00814-2
Çevresel Mikrobiyom
Intensive flooding enhances methane but reduces carbon dioxide and nitrous oxide emissions in reservoir drawdown areas. Shi, W., Delgado-Baquerizo, M., Liao, H., Gong, Y., Zhou, G., Li, S., ... & Zhang, Q. (2025). Environmental Research, 123563. https://doi.org/10.1016/j.envres.2025.123563
Sediment microbiome in reclaimed water-influenced rivers insensitive to trace sulfonamides: Implications for antibiotic risk assessment. Palomo, A., Ma, Y., Dechesne, A., Aamand, J., & Zheng, Y. (2025). Ecological Frontiers. https://doi.org/10.1016/j.ecofro.2025.12.009
Agricultural land use shapes short and long‑term bacterial diversity, community structure, and assembly in biofilms of adjacent streams. Martínez-Cuesta, R., Hoess, R., Floßmann, S., Geist, J., Dannenmann, M., Schloter, M., & Schulz, S. (2025). Environmental Microbiome. https://doi.org/10.1186/s40793-025-00837-9
Diversity loss of soil microbiome stimulates soil carbon emissions. Pan, H., Fu, Y., Tu, H., Cui, Y., Chen, B., Qi, J., Peng, Z., Chen, S., Liang, C., Liu, J., Li, X., Gao, M., Luo, Y., Wei, G., & Jiao, S. (2025). Soil Biology and Biochemistry, 110074. https://doi.org/10.1016/j.soilbio.2025.110074
Yeni Yöntemler
OmicsQ: a user-friendly platform for interactive quantitative omics data analysis. Xuan-Tung Trinh, André Abrantes da Costa, David Bouyssié, Adelina Rogowska-Wrzesinska, Veit Schwämmle. (2025). Bioinformatics. https://doi.org/10.1093/bioinformatics/btaf660
Phylo-Spec: a phylogeny-fusion deep learning model advances microbiome status identification. Zhang J, Meng F, Sun Y, Xu W, Wu S, Su X. (2025). mSystems,. https://doi.org/10.1128/msystems.01453-25
ARKbase: antimicrobial resistance knowledgebase 1.0. Simran Gambhir, Shweta Pandey, Harsh Bajetha, Jasleen Kaur, Ankita Das, Gnanasekar Pranavathiyani, Rupali Aggarwal, Upasana Maity, Suhani Dange, Vipin Singh, Mayur Zarkar, Raghav Sankhdher, Bhupender Singh, Shivani Seth, Anshu Bhardwaj. (2025). Nucleic Acids Research. https://doi.org/10.1093/nar/gkaf1307
VirJenDB: a FAIR (meta)data and bioinformatics platform for all viruses. Shahram Saghaei, Malte Siemers, Kilian L Ossetek, Stephan Richter, Robert A Edwards, Simon Roux, Andrzej Zielezinski, Bas E Dutilh, Manja Marz, Noriko A Cassman. (2025). Nucleic Acids Research. https://doi.org/10.1093/nar/gkaf1224